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Analysis of Partial Recombinants in Lentiviral Vector Preparations

The presence of replication-competent lentivirus (RCL) in lentiviral vector preparations is a major safety concern for clinical applications of such vectors. RCL are believed to emerge from rare recombinant vector genomes that are referred to as partial recombinants or Psi-Gag recombinants. To quant...

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Bibliografiske detaljer
Main Authors: Kuate, Seraphin, Marino, Michael P., Reiser, Jakob
Format: Artigo
Sprog:Inglês
Udgivet: Mary Ann Liebert, Inc. 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991964/
https://ncbi.nlm.nih.gov/pubmed/24367910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2013.015
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