The Role of Backbone Hydrogen Bonds in the Transition State for Protein Folding of a PDZ Domain

Backbone hydrogen bonds are important for the structure and stability of proteins. However, since conventional site-directed mutagenesis cannot be applied to perturb the backbone, the contribution of these hydrogen bonds in protein folding and stability has been assessed only for a very limited set...

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Bibliografiske detaljer
Main Authors: Pedersen, Søren W., Hultqvist, Greta, Strømgaard, Kristian, Jemth, Per
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991670/
https://ncbi.nlm.nih.gov/pubmed/24748272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095619
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