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HIV-1 Nef Inhibits Protease Activity and Its Absence Alters Protein Content of Mature Viral Particles

Nef is an important player for viral infectivity and AIDS progression, but the mechanisms involved are not completely understood. It was previously demonstrated that Nef interacts with GagPol through p6*-Protease region. Because p6* and Protease are involved in processing, we explored the effect of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mendonça, Luiza M., Poeys, Sandro C., Abreu, Celina M., Tanuri, Amilcar, Costa, Luciana J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991643/
https://ncbi.nlm.nih.gov/pubmed/24748174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095352
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