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Nef association with human immunodeficiency virus type 1 virions and cleavage by the viral protease.

Nef is a regulatory gene product of human immunodeficiency virus type 1 (HIV-1) and other primate lentiviruses which enhances virion infectivity by an unknown mechanism. We report here that Nef is detectable at moderate levels in preparations of HIV-1 virions which lack active viral protease (PR). S...

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Autores principales: Bukovsky, A A, Dorfman, T, Weimann, A, Göttlinger, H G
Formato: Artigo
Lenguaje:Inglês
Publicado: 1997
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC191151/
https://ncbi.nlm.nih.gov/pubmed/8995620
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