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Nef association with human immunodeficiency virus type 1 virions and cleavage by the viral protease.

Nef is a regulatory gene product of human immunodeficiency virus type 1 (HIV-1) and other primate lentiviruses which enhances virion infectivity by an unknown mechanism. We report here that Nef is detectable at moderate levels in preparations of HIV-1 virions which lack active viral protease (PR). S...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Bukovsky, A A, Dorfman, T, Weimann, A, Göttlinger, H G
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC191151/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8995620/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.71.2.1013-1018.1997
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