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Properties of avian retrovirus particles defective in viral protease.

The structural and enzymatic components of retroviral cores are formed by proteolytic cleavage of precursor polypeptides, mediated by the viral protease (PR). We constructed an active-site mutation, D37I, in the PR of avian leukosis virus. The D37I mutation was introduced into an infectious DNA clon...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Stewart, L, Schatz, G, Vogt, V M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248000/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1697912/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.10.5076-5092.1990
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