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Structural basis for translocation by AddAB helicase/nuclease and its arrest at Chi sites
In bacterial cells, processing of double-stranded DNA breaks for repair by homologous recombination is dependent upon the recombination hotspot sequence Chi(1,2) and is catalysed by either an AddAB or RecBCD-type helicase-nuclease (reviewed in refs 3, 4). These enzyme complexes unwind and digest the...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3991583/ https://ncbi.nlm.nih.gov/pubmed/24670664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13037 |
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