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Design and implementation of adoptive therapy with chimeric antigen receptor-modified T cells
A major advance in adoptive T-cell therapy (ACT) is the ability to efficiently endow patient’s T cells with reactivity for tumor antigens through the stable or regulated introduction of genes that encode high affinity tumor-targeting T-cell receptors (TCRs) or synthetic chimeric antigen receptors (C...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3991306/ https://ncbi.nlm.nih.gov/pubmed/24329794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12139 |
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