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Novel signaling axis in CML-initiating cells

In this issue of Blood, Kobayashi et al demonstrate that CD25, the α-chain of the interleukin-2 receptor (IL2RA), is expressed by certain cells that initiate chronic myeloid leukemia (CML) in a mouse model and that the IL-2/CD25 signaling axis supports CML development.(1)

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Podrobná bibliografie
Hlavní autor: Zhang, Cheng Cheng
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990909/
https://ncbi.nlm.nih.gov/pubmed/24744248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-03-560359
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