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Targeting the JAK2-STAT5 pathway in CML
In this issue of Blood, Gallipoli et al show that combined targeting of BCR/ABL1 and Janus kinase 2 (JAK2) by 2 established kinase inhibitors, nilotinib (NI) and the JAK1/2 kinase inhibitor ruxolitinib (RUX), results in synergistic growth inhibition in immature CD34(+) stem and progenitor cells obta...
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| 主要作者: | |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society of Hematology
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4148757/ https://ncbi.nlm.nih.gov/pubmed/25170113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-07-585943 |
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