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Novel signaling axis in CML-initiating cells
In this issue of Blood, Kobayashi et al demonstrate that CD25, the α-chain of the interleukin-2 receptor (IL2RA), is expressed by certain cells that initiate chronic myeloid leukemia (CML) in a mouse model and that the IL-2/CD25 signaling axis supports CML development.(1)
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3990909/ https://ncbi.nlm.nih.gov/pubmed/24744248 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-03-560359 |
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