A 20-Amino-Acid Deletion in the Neuraminidase Stalk and a Five-Amino-Acid Deletion in the NS1 Protein Both Contribute to the Pathogenicity of H5N1 Avian Influenza Viruses in Mallard Ducks

Since 2003, H5N1-subtype avian influenza viruses (AIVs) with both a deletion of 20 amino acids in the stalk of the neuraminidase (NA) glycoprotein (A−) and a deletion of five amino acids at positions 80 to 84 in the non-structural protein NS1 (S−) have become predominant. To understand the influence...

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Main Authors: Li, Yanfang, Chen, Sujuan, Zhang, Xiaojian, Fu, Qiang, Zhang, Zhiye, Shi, Shaohua, Zhu, Yinbiao, Gu, Min, Peng, Daxin, Liu, Xiufan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990698/
https://ncbi.nlm.nih.gov/pubmed/24743258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095539
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