An Amino Acid in the Stalk Domain of N1 Neuraminidase Is Critical for Enzymatic Activity

Neuraminidase (NA) is a sialidase expressed on the surface of influenza A viruses that releases progeny viruses from the surface of infected cells and prevents viruses becoming trapped in mucus. It is a homotetramer, with each monomer consisting of a transmembrane region, a stalk, and a globular hea...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zanin, Mark, Duan, Susu, Wong, Sook-San, Kumar, Gyanendra, Baviskar, Pradyumna, Collin, Emily, Russell, Charles, Barman, Subrata, Hause, Benjamin, Webby, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5215329/
https://ncbi.nlm.nih.gov/pubmed/27847354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00868-16
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