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Conditional Reverse Tet-Transactivator Mouse Strains for the Efficient Induction of TRE-Regulated Transgenes in Mice

Tetracycline or doxycycline (dox)-regulated control of genetic elements allows inducible, reversible and tissue specific regulation of gene expression in mice. This approach provides a means to investigate protein function in specific cell lineages and at defined periods of development and disease....

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Bibliographic Details
Main Authors: Dow, Lukas E., Nasr, Zeina, Saborowski, Michael, Ebbesen, Saya H., Manchado, Eusebio, Tasdemir, Nilgun, Lee, Teresa, Pelletier, Jerry, Lowe, Scott W.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990578/
https://ncbi.nlm.nih.gov/pubmed/24743474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0095236
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