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Constrained Selected Reaction Monitoring: Quantification of selected post-translational modifications and protein isoforms

Selected reaction monitoring (SRM) is a mass spectrometry method that can target signature peptides to provide for the detection and quantitation of specific proteins in complex biological samples. When quantifying a protein, peptides are generated using a specific protease such as trypsin, allowing...

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Detalhes bibliográficos
Main Authors: Liu, Xiaoqian, Jin, Zhicheng, O’Brien, Richard, Bathon, Joan, Dietz, Harry C., Grote, Eric, Van Eyk, Jennifer E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3990191/
https://ncbi.nlm.nih.gov/pubmed/23523700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.03.006
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