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Structural Basis of Substrate Recognition in Human Nicotinamide N-Methyltransferase

Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide, pyridines and other analogs using S-adenosyl-L-methionine as donor. NNMT plays a significant role in the regulation of metabolic pathways and is expressed at markedly high levels in several kinds of cancers, present...

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Bibliografiska uppgifter
Huvudupphovsmän: Peng, Yi, Sartini, Davide, Pozzi, Valentina, Wilk, Dennis, Emanuelli, Monica, Yee, Vivien C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989893/
https://ncbi.nlm.nih.gov/pubmed/21823666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2007614
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