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Structural Basis of Substrate Recognition in Human Nicotinamide N-Methyltransferase
Nicotinamide N-methyltransferase (NNMT) catalyzes the N-methylation of nicotinamide, pyridines and other analogs using S-adenosyl-L-methionine as donor. NNMT plays a significant role in the regulation of metabolic pathways and is expressed at markedly high levels in several kinds of cancers, present...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989893/ https://ncbi.nlm.nih.gov/pubmed/21823666 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi2007614 |
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