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S-glutathionylation of cryptic cysteines enhances titin elasticity by blocking protein folding
The giant elastic protein titin is a determinant factor in how much blood fills the left ventricle during diastole, and thus in the etiology of heart disease. Titin has been identified as a target of S-glutathionylation, an end product of the nitric oxide signaling cascade that increases cardiac mus...
Gorde:
| Egile Nagusiak: | , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2014
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989842/ https://ncbi.nlm.nih.gov/pubmed/24630725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.01.056 |
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