Protein Phosphatase 1 Recruitment by Rif1 Regulates DNA Replication Origin Firing by Counteracting DDK Activity

The firing of eukaryotic origins of DNA replication requires CDK and DDK kinase activities. DDK, in particular, is involved in setting the temporal program of origin activation, a conserved feature of eukaryotes. Rif1, originally identified as a telomeric protein, was recently implicated in specifyi...

Full description

Saved in:
Bibliographic Details
Main Authors: Davé, Anoushka, Cooley, Carol, Garg, Mansi, Bianchi, Alessandro
Format: Artigo
Language:Inglês
Published: Cell Press 2014
Subjects:
Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989773/
https://ncbi.nlm.nih.gov/pubmed/24656819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.02.019
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items