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Tel1(ATM) dictates the replication timing of short yeast telomeres

Telomerase action is temporally linked to DNA replication. Although yeast telomeres are normally late replicating, telomere shortening leads to early firing of subtelomeric DNA replication origins. We show that double-strand breaks flanked by short telomeric arrays cause origin firing early in S pha...

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Publicat a:EMBO Rep
Autors principals: Cooley, Carol, Davé, Anoushka, Garg, Mansi, Bianchi, Alessandro
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4253850/
https://ncbi.nlm.nih.gov/pubmed/25122631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439242
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