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Origin plasticity during budding yeast DNA replication in vitro
The separation of DNA replication origin licensing and activation in the cell cycle is essential for genome stability across generations in eukaryotic cells. Pre-replicative complexes (pre-RCs) license origins by loading Mcm2-7 complexes in inactive form around DNA. During origin firing in S phase,...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989655/ https://ncbi.nlm.nih.gov/pubmed/24566988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201387278 |
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