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Origin plasticity during budding yeast DNA replication in vitro

The separation of DNA replication origin licensing and activation in the cell cycle is essential for genome stability across generations in eukaryotic cells. Pre-replicative complexes (pre-RCs) license origins by loading Mcm2-7 complexes in inactive form around DNA. During origin firing in S phase,...

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Bibliografiska uppgifter
Huvudupphovsmän: Gros, Julien, Devbhandari, Sujan, Remus, Dirk
Materialtyp: Artigo
Språk:Inglês
Publicerad: Blackwell Publishing Ltd 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989655/
https://ncbi.nlm.nih.gov/pubmed/24566988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201387278
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