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Treg and CTLA-4: Two intertwining pathways to immune tolerance

Both the CTLA-4 pathway and regulatory T cells (Treg) are essential for the control of immune homeostasis. Their therapeutic relevance is highlighted by the increasing use of anti-CTLA-4 antibody in tumor therapy and the development of Treg cell transfer strategies for use in autoimmunity and transp...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Walker, Lucy S.K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Academic Press 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989116/
https://ncbi.nlm.nih.gov/pubmed/23849743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2013.06.006
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