Cargando...
An induced rebinding model of antigen discrimination()
T cells have to detect rare high-affinity ‘foreign’ peptide MHC (pMHC) ligands among abundant low-affinity ‘self’-peptide MHC ligands. It remains unclear how this remarkable discrimination is achieved. Kinetic proofreading mechanisms can provide the required specificity but only at the expense of mu...
Gardado en:
| Main Authors: | , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier Science Ltd
2014
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3989030/ https://ncbi.nlm.nih.gov/pubmed/24636916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2014.02.002 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|