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The Folding of a Family of Three-Helix Bundle Proteins: Spectrin R15 Has a Robust Folding Nucleus, Unlike Its Homologous Neighbours()

Three homologous spectrin domains have remarkably different folding characteristics. We have previously shown that the slow-folding R16 and R17 spectrin domains can be altered to resemble the fast folding R15, in terms of speed of folding (and unfolding), landscape roughness and folding mechanism, s...

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Detalhes bibliográficos
Main Authors: Kwa, Lee Gyan, Wensley, Beth G., Alexander, Crispin G., Browning, Stuart J., Lichman, Benjamin R., Clarke, Jane
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988883/
https://ncbi.nlm.nih.gov/pubmed/24373753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.12.018
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