Various applications of TALEN- and CRISPR/Cas9-mediated homologous recombination to modify the Drosophila genome

Modifying the genomes of many organisms is becoming as easy as manipulating DNA in test tubes, which is made possible by two recently developed techniques based on either the customizable DNA binding protein, TALEN, or the CRISPR/Cas9 system. Here, we describe a series of efficient applications deri...

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Detalhes bibliográficos
Main Authors: Yu, Zhongsheng, Chen, Hanqing, Liu, Jiyong, Zhang, Hongtao, Yan, Yan, Zhu, Nannan, Guo, Yawen, Yang, Bo, Chang, Yan, Dai, Fei, Liang, Xuehong, Chen, Yixu, Shen, Yan, Deng, Wu-Min, Chen, Jianming, Zhang, Bo, Li, Changqing, Jiao, Renjie
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988796/
https://ncbi.nlm.nih.gov/pubmed/24659249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20147682
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