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miR-34 cooperates with p53 in suppression of prostate cancer by joint regulation of stem cell compartment
MicroRNAs of miR-34 family have been originally identified as direct transactivation target of p53 and are putative tumor suppressors. Surprisingly, mice lacking all mir-34 genes show no increase in cancer formation by 18 months of age, hence placing in doubt physiological relevance of previous stud...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3988786/ https://ncbi.nlm.nih.gov/pubmed/24630988 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.02.023 |
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