Rapamycin Regulates iTreg Function through CD39 and Runx1 Pathways

It has been shown that rapamycin is able to significantly increase the expression of FoxP3 and suppress activity in induced Treg (iTreg) cells in vivo and in vitro. CD39 is a newly determined Treg marker that relates to cell suppression. Runx1, a regulator of FoxP3, controls the expression of adenos...

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Autors principals: Lu, Yunjie, Wang, Jirong, Gu, Jian, Lu, Hao, Li, Xiangcheng, Qian, Xiaofeng, Liu, Xiaoshan, Wang, Xuehao, Zhang, Feng, Lu, Ling
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988749/
https://ncbi.nlm.nih.gov/pubmed/24741640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/989434
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