Obese donor mice splenocytes aggravated the pathogenesis of acute graft-versus-host disease via regulating differentiation of Tregs and CD4(+) T cell induced-type I inflammation

Acute graft-versus-host disease (aGVHD) remains one of the most severe complications in organ and bone marrow transplantation, leading to much morbidity and mortality. Obesity has been associated with increased risk of development of various inflammatory diseases. Here, we investigated the in vitro...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Li, Zengyao, Gu, Jian, Zhu, Qin, Liu, Jing, Lu, Hao, Lu, Yunjie, Wang, Xuehao
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5650386/
https://ncbi.nlm.nih.gov/pubmed/29088831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20425
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