HDAC Inhibitors Restore the Capacity of Aged Mice to Respond to Haloperidol through Modulation of Histone Acetylation

Antipsychotic drugs are widely prescribed to elderly patients for the treatment of a variety of psychopathological conditions, including psychosis and the behavioral disturbances associated with dementia. However, clinical experience suggests that these drugs may be less efficacious in the elderly i...

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Autors principals: Montalvo-Ortiz, Janitza L, Keegan, Jack, Gallardo, Christopher, Gerst, Nicolas, Tetsuka, Kazuhiro, Tucker, Chris, Matsumoto, Mitsuyuki, Fang, Deyu, Csernansky, John G, Dong, Hongxin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988551/
https://ncbi.nlm.nih.gov/pubmed/24366052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.346
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