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ASK1 promotes the contact hypersensitivity response through IL-17 production

Contact hypersensitivity (CHS) is a form of delayed-type hypersensitivity triggered by the response to reactive haptens (sensitization) and subsequent challenge (elicitation). Here, we show that ASK1 promotes CHS and that suppression of ASK1 during the elicitation phase is sufficient to attenuate CH...

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Autors principals: Mizukami, Junya, Sato, Takehiro, Camps, Montserrat, Ji, Hong, Rueckle, Thomas, Swinnen, Dominique, Tsuboi, Ryoji, Takeda, Kohsuke, Ichijo, Hidenori
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988482/
https://ncbi.nlm.nih.gov/pubmed/24736726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04714
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