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ASK1 promotes the contact hypersensitivity response through IL-17 production

Contact hypersensitivity (CHS) is a form of delayed-type hypersensitivity triggered by the response to reactive haptens (sensitization) and subsequent challenge (elicitation). Here, we show that ASK1 promotes CHS and that suppression of ASK1 during the elicitation phase is sufficient to attenuate CH...

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Detalhes bibliográficos
Main Authors: Mizukami, Junya, Sato, Takehiro, Camps, Montserrat, Ji, Hong, Rueckle, Thomas, Swinnen, Dominique, Tsuboi, Ryoji, Takeda, Kohsuke, Ichijo, Hidenori
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988482/
https://ncbi.nlm.nih.gov/pubmed/24736726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04714
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