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Synaptic Glutamate Spillover Due to Impaired Glutamate Uptake Mediates Heroin Relapse

Reducing the enduring vulnerability to relapse is a therapeutic goal in treating drug addiction. Studies with animal models of drug addiction show a marked increase in extrasynaptic glutamate in the core subcompartment of the nucleus accumbens (NAcore) during reinstated drug seeking. However, the sy...

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Bibliografski detalji
Glavni autori: Shen, Hao-wei, Scofield, Michael D., Boger, Heather, Hensley, Megan, Kalivas, Peter W.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988415/
https://ncbi.nlm.nih.gov/pubmed/24741055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4564-13.2014
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