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Synaptic plasticity mediating cocaine relapse requires matrix metalloproteinases
Relapse to cocaine use necessitates remodeling excitatory synapses in the nucleus accumbens, and synaptic reorganization requires matrix metalloproteinase (MMP) degradation of the extracellular matrix proteins. We found enduring increases in MMP-2 activity in rats after withdrawal from self-administ...
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| Publicado no: | Nat Neurosci |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4241163/ https://ncbi.nlm.nih.gov/pubmed/25326689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3846 |
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