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Synaptic plasticity mediating cocaine relapse requires matrix metalloproteinases
Relapse to cocaine use necessitates remodeling excitatory synapses in the nucleus accumbens, and synaptic reorganization requires matrix metalloproteinase (MMP) degradation of the extracellular matrix proteins. We found enduring increases in MMP-2 activity in rats after withdrawal from self-administ...
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| 發表在: | Nat Neurosci |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4241163/ https://ncbi.nlm.nih.gov/pubmed/25326689 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3846 |
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