The N-Terminal Methionine of Cellular Proteins as a Degradation Signal

The Arg/N-end rule pathway targets for degradation proteins that bear specific unacetylated N-terminal residues while the Ac/N-end rule pathway targets proteins through their N(α)-terminally acetylated (Nt-acetylated) residues. Here we show that Ubr1, the ubiquitin ligase of the Arg/N-end rule pathw...

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Huvudupphovsmän: Kim, Heon-Ki, Kim, Ryu-Ryun, Oh, Jang-Hyun, Cho, Hanna, Varshavsky, Alexander, Hwang, Cheol-Sang
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2013
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988316/
https://ncbi.nlm.nih.gov/pubmed/24361105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.11.031
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