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The N-Terminal Methionine of Cellular Proteins as a Degradation Signal
The Arg/N-end rule pathway targets for degradation proteins that bear specific unacetylated N-terminal residues while the Ac/N-end rule pathway targets proteins through their N(α)-terminally acetylated (Nt-acetylated) residues. Here we show that Ubr1, the ubiquitin ligase of the Arg/N-end rule pathw...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3988316/ https://ncbi.nlm.nih.gov/pubmed/24361105 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.11.031 |
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