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Induced pluripotent stem cells generated without viral integration

Pluripotent stem cells have been generated from mouse and human somatic cells by viral expression of the transcription factors Oct4, Sox2, Klf4, and c-Myc. A major limitation of this technology is the use of potentially harmful genome-integrating viruses. Here, we generate mouse induced pluripotent...

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Detaylı Bibliyografya
Asıl Yazarlar: Stadtfeld, Matthias, Nagaya, Masaki, Utikal, Jochen, Weir, Gordon, Hochedlinger, Konrad
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987909/
https://ncbi.nlm.nih.gov/pubmed/18818365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1162494
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