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A high efficiency system for the generation and study of human induced pluripotent stem cells
Direct reprogramming of human fibroblasts to a pluripotent state has been achieved through ectopic expression of the transcription factors OCT4, SOX2, and either cMYC and KLF4 or NANOG and LIN28. Little is known, however, about the mechanisms by which reprogramming occurs, which is in part limited b...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3987901/ https://ncbi.nlm.nih.gov/pubmed/18786420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2008.08.003 |
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