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CP110 Suppresses Primary Cilia Formation through its Interaction with CEP290, a Protein Deficient in Human Ciliary Disease

Primary cilia are non-motile organelles implicated in signaling and sensory functions. Understanding how primary cilia assemble could shed light on the many human diseases caused by mutations in ciliary proteins. The centrosomal protein CP110 is known to suppress ciliogenesis through an unknown mech...

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Autors principals: Tsang, William Y., Bossard, Carine, Khanna, Hemant, Peranen, Johan, Swaroop, Anand, Malhotra, Vivek, Dynlacht, Brian David
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987787/
https://ncbi.nlm.nih.gov/pubmed/18694559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.07.004
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