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CP110 Suppresses Primary Cilia Formation through its Interaction with CEP290, a Protein Deficient in Human Ciliary Disease

Primary cilia are non-motile organelles implicated in signaling and sensory functions. Understanding how primary cilia assemble could shed light on the many human diseases caused by mutations in ciliary proteins. The centrosomal protein CP110 is known to suppress ciliogenesis through an unknown mech...

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Bibliografiske detaljer
Main Authors: Tsang, William Y., Bossard, Carine, Khanna, Hemant, Peranen, Johan, Swaroop, Anand, Malhotra, Vivek, Dynlacht, Brian David
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3987787/
https://ncbi.nlm.nih.gov/pubmed/18694559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.07.004
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