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Nephrocystin proteins NPHP5 and Cep290 regulate BBSome integrity, ciliary trafficking and cargo delivery

Proper functioning of cilia, hair-like structures responsible for sensation and locomotion, requires nephrocystin-5 (NPHP5) and a multi-subunit complex called the Bardet–Biedl syndrome (BBS)ome, but their precise relationship is not understood. The BBSome is involved in the trafficking of membrane c...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Barbelanne, Marine, Hossain, Delowar, Chan, David Puth, Peränen, Johan, Tsang, William Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380068/
https://ncbi.nlm.nih.gov/pubmed/25552655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu738
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