Activation of Inflammasomes in Podocyte Injury of Mice on the High Fat Diet: Effects of ASC Gene Deletion and Silencing

Inflammasome, an intracellular inflammatory machinery, has been reported to be involved in a variety of chronic degenerative diseases such as atherosclerosis, autoinflammatory diseases and Alzheimer’s disease. The present study hypothesized that the formation and activation of inflammasomes associat...

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Bibliographic Details
Main Authors: Boini, Krishna M., Xia, Min, Abais, Justin M., Li, Guangbi, Pitzer, Ashley L., Gehr, Todd W. B., Zhang, Yang, Li, Pin-Lan
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986924/
https://ncbi.nlm.nih.gov/pubmed/24508291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2014.01.033
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