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Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation

Type I interferons (IFNs) form a network of homologous cytokines that bind to a shared, heterodimeric cell surface receptor and engage signaling pathways that activate innate and adaptive immune responses. The ability of IFNs to mediate differential responses through the same cell surface receptor h...

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Autors principals: Piehler, Jacob, Thomas, Christoph, Garcia, K. Christopher, Schreiber, Gideon
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986811/
https://ncbi.nlm.nih.gov/pubmed/23046138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12001
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