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Structural and dynamic determinants of type I interferon receptor assembly and their functional interpretation

Type I interferons (IFNs) form a network of homologous cytokines that bind to a shared, heterodimeric cell surface receptor and engage signaling pathways that activate innate and adaptive immune responses. The ability of IFNs to mediate differential responses through the same cell surface receptor h...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Piehler, Jacob, Thomas, Christoph, Garcia, K. Christopher, Schreiber, Gideon
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986811/
https://ncbi.nlm.nih.gov/pubmed/23046138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12001
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