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The molecular basis for differential type I interferon signaling
Type I interferons (IFN-1) are cytokines that affect the expression of thousands of genes, resulting in profound cellular changes. IFN-1 activates the cell by dimerizing its two-receptor chains, IFNAR1 and IFNAR2, which are expressed on all nucleated cells. Despite a similar mode of binding, the dif...
Uloženo v:
| Vydáno v: | J Biol Chem |
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| Hlavní autor: | |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5418031/ https://ncbi.nlm.nih.gov/pubmed/28289098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R116.774562 |
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