8-oxoguanine causes spontaneous de novo germline mutations in mice

Spontaneous germline mutations generate genetic diversity in populations of sexually reproductive organisms, and are thus regarded as a driving force of evolution. However, the cause and mechanism remain unclear. 8-oxoguanine (8-oxoG) is a candidate molecule that causes germline mutations, because i...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Ohno, Mizuki, Sakumi, Kunihiko, Fukumura, Ryutaro, Furuichi, Masato, Iwasaki, Yuki, Hokama, Masaaki, Ikemura, Toshimichi, Tsuzuki, Teruhisa, Gondo, Yoichi, Nakabeppu, Yusaku
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986730/
https://ncbi.nlm.nih.gov/pubmed/24732879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04689
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki