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CKMT1 regulates the mitochondrial permeability transition pore in a process that provides evidence for alternative forms of the complex

The permeability transition pore (PT-pore) mediates cell death through the dissipation of the mitochondrial membrane potential (ΔΨ(m)). Because the exact composition of the PT-pore is controversial, it is crucial to investigate the actual molecular constituents and regulators of this complex. We fou...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Datler, Christoph, Pazarentzos, Evangelos, Mahul-Mellier, Anne-Laure, Chaisaklert, Wanwisa, Hwang, Ming-Shih, Osborne, Foy, Grimm, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986677/
https://ncbi.nlm.nih.gov/pubmed/24522192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.140467
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