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Telomerase Protects Werner Syndrome Lineage-Specific Stem Cells from Premature Aging
Werner syndrome (WS) patients exhibit premature aging predominantly in mesenchyme-derived tissues, but not in neural lineages, a consequence of telomere dysfunction and accelerated senescence. The cause of this lineage-specific aging remains unknown. Here, we document that reprogramming of WS fibrob...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3986587/ https://ncbi.nlm.nih.gov/pubmed/24749076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.02.006 |
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