Chymase Mediates Injury and Mitochondrial Damage in Cardiomyocytes during Acute Ischemia/Reperfusion in the Dog

Cardiac ischemia and reperfusion (I/R) injury occurs because the acute increase in oxidative/inflammatory stress during reperfusion culminates in the death of cardiomyocytes. Currently, there is no drug utilized clinically that attenuates I/R injury in patients. Previous studies have demonstrated de...

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Dettagli Bibliografici
Autori principali: Zheng, Junying, Wei, Chih-Chang, Hase, Naoki, Shi, Ke, Killingsworth, Cheryl R., Litovsky, Silvio H., Powell, Pamela C., Kobayashi, Tsunefumi, Ferrario, Carlos M., Rab, Andras, Aban, Inmaculada, Collawn, James F., Dell'Italia, Louis J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986229/
https://ncbi.nlm.nih.gov/pubmed/24733352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094732
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