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Dissociation between cardiomyocyte function and remodeling with β-adrenergic receptor blockade in isolated canine mitral regurgitation
The low-pressure volume overload of isolated mitral regurgitation (MR) is associated with increased adrenergic drive, left ventricular (LV) dilatation, and loss of interstitial collagen. We tested the hypothesis that β(1)-adrenergic receptor blockade (β(1)-RB) would attenuate LV remodeling after 4 m...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614546/ https://ncbi.nlm.nih.gov/pubmed/18849331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00746.2008 |
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