Microarray Identifies Extensive Downregulation of Noncollagen Extracellular Matrix and Profibrotic Growth Factor Genes in Chronic Isolated Mitral Regurgitation in the Dog

BACKGROUND: The volume overload of isolated mitral regurgitation (MR) in the dog results in left ventricular (LV) dilatation and interstitial collagen loss. To better understand the mechanism of collagen loss we performed a gene array and overlaid regulated genes into Ingenuity Pathway Analysis (IPA...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Zheng, Junying, Chen, Yuanwen, Pat, Betty, Dell’Italia, Louis A, Tillson, Michael, Dillon, A Ray, Powell, Pamela, Shi, Ke, Shah, Neil, Denney, Thomas, Husain, Ahsan, Dell’Italia, Louis J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092370/
https://ncbi.nlm.nih.gov/pubmed/19349319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.108.826230
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky