Dissociation between cardiomyocyte function and remodeling with β-adrenergic receptor blockade in isolated canine mitral regurgitation

The low-pressure volume overload of isolated mitral regurgitation (MR) is associated with increased adrenergic drive, left ventricular (LV) dilatation, and loss of interstitial collagen. We tested the hypothesis that β(1)-adrenergic receptor blockade (β(1)-RB) would attenuate LV remodeling after 4 m...

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Hlavní autoři: Pat, Betty, Killingsworth, Cheryl, Denney, Thomas, Zheng, Junying, Powell, Pamela, Tillson, Michael, Dillon, A. Ray, Dell'Italia, Louis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2008
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614546/
https://ncbi.nlm.nih.gov/pubmed/18849331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00746.2008
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